INTERFACIAL INSIGHTS: [6]-GINGEROL MONOLAYERS AT THE AIR-WATER INTERFACE AND BEYOND

Interfacial insights: [6]-Gingerol monolayers at the air-water interface and beyond

Interfacial insights: [6]-Gingerol monolayers at the air-water interface and beyond

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Ginger is a culinary spice with a millennia-old tradition due to its extensive therapeutic applications, recently validated by scientific studies.In particular [6]-Gingerol, a key active molecule in ginger, exhibits extraordinary capabilities in addressing a wide spectrum of health issues.However, its therapeutic potential is limited by its rather low bioavailability.The incorporation of [6]-Gingerol into membrane systems of liposomes, micelles, or exosomes is a promising strategy to overcome this limitation.

In this contribution, we report the read more hitherto unexplored surface properties of [6]-Gingerol at the air-water interface.Our comprehensive study, which includes a detailed analysis of surface pressure and surface potential vs.area per molecule isotherms, surface compression modulus, and Brewster Angle Microscopy, demonstrates the capability of [6]-Gingerol to form Langmuir films.These films can be transferred onto solid substrates, forming remarkably homogeneous Langmuir-Blodgett films which have been characterized by Quartz Crystal Microbalance and Atomic Force Microscopy.

This study may be of interest as it paves the tokidoki hello kitty blind box way for future research on introducing [6]-Gingerol into membrane systems and transporting it into living cells.

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